Comments on: Responding to Criticism- Phadia Immunocap Testing http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/ Pediatric Allergist Frederick E. Leickly - Indianapolis, Indiana Wed, 01 Feb 2012 20:04:37 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: fleickly http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-805 fleickly Sun, 11 Jul 2010 16:56:24 +0000 http://www.leicklystory.com/?p=518#comment-805 Given the crudeness of the diagnostic tests currently available for determining IgE to peanut, I think this new technology may help sort things out. I have been reviewing all the peanut positive children we have seen since January, 2009 to date. There are about 350 who have had a positive peanut skin test. Their histories of clinical reactivity range from anaphylaxis to contact urticaria to having no reactions at all (they have eaten peanut have had no problems, but have that positive test). I have seen that article. Thanks for referencing it and thanks for the comments. FEL Given the crudeness of the diagnostic tests currently available for determining IgE to peanut, I think this new technology may help sort things out. I have been reviewing all the peanut positive children we have seen since January, 2009 to date. There are about 350 who have had a positive peanut skin test. Their histories of clinical reactivity range from anaphylaxis to contact urticaria to having no reactions at all (they have eaten peanut have had no problems, but have that positive test).
I have seen that article. Thanks for referencing it and thanks for the comments.
FEL

]]> By: Karim Mourabit Amari http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-804 Karim Mourabit Amari Sun, 11 Jul 2010 16:23:44 +0000 http://www.leicklystory.com/?p=518#comment-804 I think component allergy testing is the possibility to test if IgE against single epitopes of an allergen is. I am reading stuff about Immunocap and as an example, for peanuts, you would have components Ara h 1, Ara h 2, Ara h 3, Ara h 8 and they could be tested individually and the resulting profile can be interpretated. From what I understand at this stage, Ara h 1,2 and 3 are the most relevant components to test in regard to peanuts allergy. I have an article which is good : http://www.ncbi.nlm.nih.gov/pubmed/20146729 IgE to peanut allergen components: relation to peanut symptoms and pollen sensitization in 8-year-olds. I think component allergy testing is the possibility to test if IgE against single epitopes of an allergen is. I am reading stuff about Immunocap and as an example, for peanuts, you would have components Ara h 1, Ara h 2, Ara h 3, Ara h 8 and they could be tested individually and the resulting profile can be interpretated. From what I understand at this stage, Ara h 1,2 and 3 are the most relevant components to test in regard to peanuts allergy.

I have an article which is good : http://www.ncbi.nlm.nih.gov/pubmed/20146729

IgE to peanut allergen components: relation to peanut symptoms and pollen sensitization in 8-year-olds.

]]> By: fleickly http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-278 fleickly Tue, 26 Jan 2010 23:53:51 +0000 http://www.leicklystory.com/?p=518#comment-278 I am glad that worked for you and your child. You also point out the importance of the history of a food exposure-your ingestion of tree nuts and shellfish. I am glad that worked for you and your child. You also point out the importance of the history of a food exposure-your ingestion of tree nuts and shellfish.

]]> By: Leslie http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-276 Leslie Tue, 26 Jan 2010 22:28:30 +0000 http://www.leicklystory.com/?p=518#comment-276 I think that if the child/infant is breastfeeding then the full allergy panel including nuts and seafood is totally appropriate. My daughter was exclusively breastfed when I had her tested at 6 months and we found out that my eating nuts and milk was the cause of her discomfort and severe eczema. Skin test confirmed her allergy. When I eliminated those foods from my diet her skin cleared and she became a much happier baby. I think that if the child/infant is breastfeeding then the full allergy panel including nuts and seafood is totally appropriate. My daughter was exclusively breastfed when I had her tested at 6 months and we found out that my eating nuts and milk was the cause of her discomfort and severe eczema. Skin test confirmed her allergy. When I eliminated those foods from my diet her skin cleared and she became a much happier baby.

]]> By: fleickly http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-206 fleickly Sun, 29 Nov 2009 15:55:18 +0000 http://www.leicklystory.com/?p=518#comment-206 Thank you for the kind words. FEL Thank you for the kind words.
FEL

]]> By: Rebecca Cooley http://www.pediatricallergyindy.com/2009/11/13/responding-to-criticism-phadia-immunocap-testing/comment-page-1/#comment-205 Rebecca Cooley Tue, 24 Nov 2009 22:46:53 +0000 http://www.leicklystory.com/?p=518#comment-205 I am sorry your "commentor" was so critical. I thought you handled your reply very well. During our first few visits with you (for my daughter) I learned a lot about allergy testing which I didn't know, and your answers all made perfect sense to me. One thing which really stood out was not to do the blood tests unless there was a good reason to do so ( a history of hives relating to a food, etc.) It's okay for people to have differing opinions -- that's part of what makes life interesting -- but use the Golden Rule (as you did). I am sorry your “commentor” was so critical. I thought you handled your reply very well. During our first few visits with you (for my daughter) I learned a lot about allergy testing which I didn’t know, and your answers all made perfect sense to me. One thing which really stood out was not to do the blood tests unless there was a good reason to do so ( a history of hives relating to a food, etc.)
It’s okay for people to have differing opinions — that’s part of what makes life interesting — but use the Golden Rule (as you did).

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